Weight-loss drugs like Ozempic and Wegovy are gaining popularity as quick fixes for shedding pounds. Known as GLP-1 agonists, these medications work by imitating a gut hormone that reduces hunger, helping people eat less and, in turn, lose weight. While they may seem like a simple solution, these drugs come with a range of drawbacks that often go unmentioned, leaving us to question if they’re truly sustainable – or even healthy – in the long run.
GLP-1 drugs may have benefits for people facing severe obesity or critical metabolic conditions, providing an option when other treatments have failed. But even for these individuals, lasting weight loss can often be achieved through natural lifestyle and dietary changes. In our work at PHD Weight Loss, we regularly see clients lose 100 pounds or more without medications. This experience shows that sustainable, effective options exist without the need for lifelong medication.
One significant concern with GLP-1 drugs is their side effects. Many users experience nausea, stomach pain and even hair loss in the short term. Longer-term risks are also emerging, with studies suggesting these drugs may increase the likelihood of serious issues like bowel obstructions and pancreatitis. Because these drugs alter hormones related to both brain and gut function, they can impact mental well-being and overall health.
Another critical issue with these medications is their effect on muscle mass. Research reveals that a large portion of the weight lost through GLP-1 drugs – up to 40% – comes from muscle rather than fat. Losing muscle is particularly damaging because muscle is essential for maintaining metabolism, strength and long-term weight loss. Especially in older adults, muscle is vital for longevity, as it burns more calories than fat and supports a healthy, active lifestyle. Drugs that deplete muscle, rather than only fat, may ultimately hinder a person’s overall health and ability to maintain weight loss.
Dependency on these drugs is also a real concern. To keep weight off, users must continue taking these medications indefinitely, with many spending up to $1,700 per month. If they stop, most people regain the weight, often in a worse state due to lost muscle and a slower metabolism. This dependency makes it costly and unsustainable in the long term.
GLP-1 drugs are often praised for reducing “food noise” – that constant urge to think about what you’ll eat next. But it’s worth noting that with the right guidance, a diet that supports metabolic flexibility/fat-adaptation and behavioral support can naturally quiet this inner chatter. By learning how to feed our bodies with the foods that truly support metabolic health, we can achieve long-lasting health and mental clarity without relying on medication.
If you or someone you know is struggling with weight, know that sustainable options are available. Achieving lasting health requires patience and commitment, but it builds true resilience and strength. With the right support, weight loss is entirely possible without medications – and the lifelong dependence they bring for most people. True wellness comes from empowering ourselves with knowledge, good habits, and a holistic approach to health.
Ashley Lucas has a doctorate in sports nutrition and chronic disease. She is also a registered dietitian nutritionist. She is the founder and owner of PHD Weight Loss and Nutrition, offering weight management and wellness services in the Four Corners. She can be reached at 764-4133.