Combining tirzepatide injections with hormone replacement therapy leads to significantly greater fat loss in many more women
NEW ORLEANS — Many of us who have tried to lose weight have been told we’re just not trying hard enough.
And for women after menopause, the newest study suggests it may be something completely out of their control.
Now there’s an update on the latest findings when it comes to those weight loss injections paired with hormone replacement.
When endocrinologists met recently for their annual meeting, a study from the Mayo Clinic made headlines. Post menopausal women who are on hormone replacement and also use tirzepatide weight loss injections will significantly increase their chances of losing a lot more weight than those only on tirzepatide.
Does this surprise you that getting both of these hormones correct makes a difference?
“No, it doesn’t because I’ve long known that when women go into post menopausal stages of their life, that they lay down this abdominal fat, and it’s almost impossible to lose. I mean, you can’t exercise your way out of it,” said Dr. Melinda Sothern, professor emeritus at LSU Health Sciences Center.
Obesity expert and researcher Dr. Sothern says that deep belly fat, as opposed to thigh and hip fat just under the skin, is more dangerous, damaging, and aging. And without hormone replacement, you also lose bone and muscle.
When you lose muscle because you don’t have your hormones, that makes your metabolism slow down because muscles are like a furnace just sitting still in your body.
“Right, right, the more muscle tissue you have in your body, the higher your energy expenditure, the more you’re going to burn calories.”
So, replacing female hormones also helps regulate your metabolism. Then adding in tripeptide, which is the brand Mounjaro and Zepbound, also helps regulate dysfunction in your metabolism.
“So, you are better able to use the food that you eat to have a normal metabolism that will be used by the muscles as fuel as opposed to being stored at the abdominal site,” said Dr. Sothern.
Tirzepatide is a weight loss and diabetes injection that mimics two natural hormones, unlike semaglutide, which is used in Ozempic and Wegovy, which only mimics one. And while more studies are needed to confirm what doctors are seeing in patient charts, it’s best to have your female hormone levels personally checked through a blood test to determine how much you need to be replaced.
Dr. Sothern also advises checking your vitamin D levels, as well as vitamins B12, B6, and B2, because all are involved in healthy metabolism.
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