In addition to muscle loss, Dr. Enayat says he’s seen new patients at his clinic who have been on GLP-1s for years without supervision who are, “showing signs of frailty, weakness, low mood, low motivation, reduced exercise tolerance. We put this down to being in a long-term calorie-deficit state.” Essentially, after spending a prolonged period of time restricting calories and nutrients, it’s not uncommon for people to find that their mental state, energy levels, and ability to exercise end up in a state of decline.
MOTS-C for weight loss: healthier, safer and cheaper than Ozempic?
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