As it turns out, Mounjaro is getting in the good books of Hollywood stars!
Amy Schumer is endorsing the ‘weight loss drug’, that too – over already existing Wegovy, which falls under the same category.
The Hollywood approval!
Amy Schumer, the well-known American comedian, actor, writer, producer, and director recently took to social media platform to share her feedback after using Mounjaro. She posted a video on Instagram, saying, “Mounjaro’s been great!”
Starting the video by quipping, “I want to commit to you that I will never get lip fillers, so you can always enjoy that I have no top lip.” Schumer made a disclaimer to ‘to keep it real’ with her fans and followers and noted that she was having “a really good experience” taking a new weight-loss drug.
Schumer then opened up about undergoing hormone replacement therapy for perimenopause as well as using weight-loss medication. The 43-year-old artist also shared that she had previously tried to lose weight with Wegovy three years ago, but experienced unpleasant symptoms, recalling, “I was like puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever.”
Schumer then went on to explain that after that experience, she scheduled a telehealth appointment and was prescribed two hormones, estrogen and progesterone, for her perimenopause symptoms. She said she also began using Mounjaro, a GLP-1 drug for type 2 diabetes that is also often prescribed for weight loss.
Schumer added that combined, all of her new medications have yielded positive results, saying, “My symptoms of being in perimenopause have disappeared. My hair is fuller, my skin is better, I have more energy. I want to ‘get down’ more, if you know what I mean,” the Kinda Pregnant star said quickly clarifying, “I’m talking about sex!”
What is Mounjaro?
Approved by the US Food and Drug Administration for type 2 diabetes and packaged as an injection, Mounjaro (tirzepatide) has already sparked discussions over its effectiveness in managing weight, with some claiming it is superior to Ozempic—the popular weight loss drug. Tirzepatide is an antidiabetic medication used to treat type 2 diabetes and for weight management and is administered via subcutaneous injections (under the skin).
In the United States, it is sold under the brand name Mounjaro for diabetes treatment and Zepbound for weight loss and treatment of obstructive sleep apnea.
What is Mounjaro used for?
Mounjaro is an injectable medicine for adults with type 2 diabetes used along with diet and exercise to improve blood sugar (glucose). It is not known if Mounjaro can be used in people who have had inflammation of the pancreas (pancreatitis). Mounjaro is not for use in people with type 1 diabetes.
How does Mounjaro work?
Mounjaro (tirzepatide) works by mimicking two gut hormones, GLP-1 and GIP, to regulate blood sugar, digestion, and appetite, leading to improved blood sugar control and potential weight loss.
Key points:
Mimicking Hormones: Mounjaro contains tirzepatide, which acts as a dual-agonist, meaning it mimics the effects of both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide).
Blood Sugar Regulation: By mimicking GLP-1, Mounjaro increases insulin release when blood sugar levels are high, helping to lower them. It also slows down the release of sugar from the liver and slows gastric emptying, preventing rapid spikes in blood sugar after meals.
Appetite and Weight Management: By mimicking both GLP-1 and GIP, Mounjaro can reduce appetite and food intake, potentially leading to weight loss. It also stimulates lipolysis, which is the breakdown of fat, further contributing to weight loss.
Are Mounjaro and Wegovy the same?
Schumer has been open about taking Wegovy, the brand name used for Semaglutide that has also been marketed under the name Ozempic, touted by many as a “miracle” weight-loss drug. In January, she appeared on The Howard Stern Show where she explained that she tried using the drug three years ago, but ended up being ‘bedridden’ as she carries a gene that makes her prone to nausea.
However, nausea is quite a common side effect of taking Wegovy and other drugs, that are used for weight loss.
While Mounjaro and Wegovy weight loss injections work in broadly the same way, they have different active ingredients. The active ingredient in Mounjaro is Tirzepatide, while the active ingredient in Wegovy is Semaglutide. Mounjaro was first approved in the UK to treat type II diabetes.
Potential benefits:
Mounjaro improves blood sugar levels, which helps lower the risk of diabetes-related complications, such as nerve damage, kidney disease, and vision loss over time. It also promotes substantial weight loss.
However, the most common side effects of Mounjaro include nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and stomach (abdominal) pain.
One must talk to their healthcare provider about any side effects that seem to bother them and do not go away.