Neuroprotection in Alzheimer’s Models
Supplementation with Moringa oleifera leaf extract in the APP/PS1 mice model of Alzheimer’s disease reduced amyloid‑β plaque accumulation, improved synaptic plasticity, and enhanced cognitive performance. According to a research published in MDPI.
Anti‑Inflammatory effects on memory
According to a study performed in rats published in OUP Academic, exposed to the neurotoxin aluminum chloride, moringa leaf extract diminished the levels of some inflammatory cytokines (such as IL‑6 and TNF‑α), enhanced the activity of antioxidant enzymes, and restored learning and memory.
Protection against brain-related ailments
In a research published in PubMed Central, mice fed a high-fat, high-fructose diet-a common model of metabolic stress-moringa leaf extract and moringa seed oil prevented signs of brain aging. Treatment lowered markers of cellular senescence (p16 and p21) and supported brain-derived neurotrophic factor (BDNF), which is important for neuron growth and repair.
Cognitive boost
In one study, conducted on the offspring of rats that were deprived of adequate protein during pregnancy, moringa extract enhanced learning and memory in the hippocampus, a part of the brain very important for spatial memory.