Stress and brain health: Neurologist reveals why your mind struggles under pressure and fatigue

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Stress reshapes your brain and nerves, impacting memory, focus, and emotional control. Prolonged stress rewires brain circuits, changes hormone levels, and affects overall health.

Stress isn’t a passing nuisance
We all know stress, those moments when life feels challenging, and our minds feel overwhelmed. But stress isn’t merely a passing nuisance; it’s a powerful force that physically changes our brain and nervous system. While short bursts can be helpful, chronic stress pushes the body into overdrive, damaging key brain areas responsible for memory, focus, and emotional balance (Images: Canva)

Stress and the brain relationship
Stress, Dr Pradyumna Oak, Senior Director of Neurology, Nanavati Max Super Speciality Hospital, Mumbai, says, isn’t “all bad,” especially in the short term. “Your body releases chemicals like adrenaline and cortisol to help you meet challenges.” He says, adding, “However, when these systems stay activated for too long, it creates what’s known as ‘allostatic load’—wear and tear that harms your health.”

Chronic stress reshapes brain circuit
The brain judges the threats and orchestrates responses via nerves, hormones, and the immune system. “Chronic stress reshapes brain circuits, especially in areas linked to memory and focus. Brain scans confirm this rewiring: some areas become less active, while others work overtime, leading to impaired decision-making and concentration.” says Dr Oak and shares how stress impacts your nerves and brain:

Stress can be helpful, only for a while
Short bursts of adrenaline and cortisol helps to respond quickly. But prolonged stress leads to weer and tear, hampering your body’s resources.

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The brain controls stress response
The brain senses danger and triggers nerves, hormones, and immune actions. Thus, shaping how your body reacts physically and mentally.

Chronic stress shrinks memory, focus
Parts like the hippocampus and prefrontal cortex shrink, leading to poorer memory and less self-control.

Neurons get remodelled by stress
Nerve cell branches shrink in vital brain regions, but the amygdala, linked to fear and anxiety grows, making you more irritable and fearful.

Sleep loss worsens stress effects
Stress often disrupts sleep, raising cortisol and blood pressure at night, increasing inflammation, and dulling mental sharpness.

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Everyone reacts to stress differently
Some are more sensitive to social pressure and deadlines, which explain why stress hits people unequally.

Inflammation affects brain health
Persistent stress triggers inflammatory signals, which damage nerves and may worsen cognitive decline.

Appetite and metabolism
Stress hormones alter hunger signals, often leading to poor nutrition that can harm brain and nerve function.

Managing stress protects brain circuits
Simple habits like mindfulness, regular sleep, and exercise can help reverse harmful brain changes and improve resilience.

Stress changes brain activity patterns
Areas that help weigh options and retain information, slowdown. While the brain’s conflict centre works harder, making focus difficult under pressure (Disclaimer: This article, including health and fitness advice, only provides generic information. Don’t treat it as a substitute for qualified medical opinion. Always consult a specialist for specific health diagnosis)

Namita S Kalla is a senior journalist who writes about different aspects of modern life that include lifestyle, health, fashion, beauty, and entertainment.

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